Download , by Alan Fersht
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, by Alan Fersht
Download , by Alan Fersht
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Product details
File Size: 19469 KB
Print Length: 656 pages
Publisher: Kaissa Publications (October 19, 2018)
Publication Date: October 19, 2018
Sold by: Amazon Digital Services LLC
Language: English
ASIN: B07JL2K6B8
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Amazon Best Sellers Rank:
#789,669 Paid in Kindle Store (See Top 100 Paid in Kindle Store)
A valuable reference, rich in graphs, tables, and citations. Chapters include topics covering the following:- catalysis- enzyme kinetics- measuring rate constants- pH dependence- equilibria- intermediates- stereochemistry- inhibition, regulation- binding energies- specificity and affinity- recombinant DNA technology- protein engineering- case studies in structure & function- stability and folding kinetics- folding and energy landscapesKnowing what it covers, I'd recommend this book only to serious undergraduates (with at least 1 year of physical chemistry and biochemistry each) or to graduate students...or diehard science literate people. Each chapter is thoroughly cited for further reading pleasure.
This book belongs in every protein biochemists collection. It is a clear, up-to-date review of protein structure and function, with a concentration on enzymes. It covers a host of vital topics, including: the theories of chemical catalysis, enzyme kinetics (buy Segal for an in-depth study of this topic), the methods for determining rate constants, the stereochemistry of enzyme reactions, various regulation mechanisms, binding energies and the forces between molecules, and an overview of protein engineering techniques. If all this were not enough, Fersht concludes with a wonderful chapter covering case studies of enzyme structure and mechanism, and another couple on the kinetics and mechanisms of protein folding. Extensive references are given to the current literature for further study.Putting all these topics into one book is an accomplishment that few authors could pull off - but Fersht does it extremely well!Oh - the other nine ?Cornish-Bowden, "Principles of Enzyme Kinetics"; Segal, "Enzyme Kinetics"; Voet & Voet, "Biochemistry"; Branden & Tooze, "Introduction to Protein Science"; Dixon & Web, "Enzymes"; Pauling, "The Nature of the Chemical Bond"; Scopes, "Protein Purification"; Freifelder, "Physical Biochemistry"; Walsh, "Enzymatic Reaction Mechanisms"
It is a good book!
Great book for those studying enzymes. Contains lots of info and is a great source for papers. I would highly recommend this book.
The book arrived fast and in a good quality.The cover and the pages are clean and without any scrawl.I am really enjoying my new book.
Delivery: Said that it would be delivered in 4 to 6 weeks but came within two weeks.Textbook quality: the textbook was not used. Except for some wear on the cover, the pages were crisp and didn't contain writing or highlighting.
The book focuses on enzyme catalysis, stereochemistry of enzyme reactions, determination of rate constant, enzyme kinetics, and protein structure and folding. It would be an ideal reference for the study of protein chemistry. It can serve as the primary text for an advanced course in protein chemistry or a supplement for undergraduate biochemistry text.Protein folding has remained one of the most intricate yet less understood process in modern biochemistry. Feersht's treatise of the subject in this book is splendid. The author overviews protein structure and diversity in the opening chapter. What I find really precious about this book is the discussion on protein engineering, forces on folding, and recombinant DNA technology in the context of protein folding.Aside from protein chemistry, the chapter on chemical catalysis is excellent in learning more about transition state theory, general acid/base catalysis, covalent catalysis, structure-reactivity relationships, and kinetic isotope effects.
If you are studying protein structure, you probably should read this book for reference.This is solely my opinion, but I have learned new things and reinforced some old knowledge, as well. The book is well-written, and understandable, without being simplistic.Some texts are difficult to understand, or dry, or facile. This is not one of those texts.
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